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TAM Receptor Tyrosine Kinases: Biologic Functions, Signaling, and Potential Therapeutic Targeting in Human Cancer

Tyro-3, Axl, and Mer constitute the TAM family of receptor tyrosine kinases (RTKs) characterized by a conserved sequence within the kinase domain and adhesion molecule-like extracellular domains. This small family of RTKs regulates an intriguing mix of processes, including cell proliferation/surviva...

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Detalhes bibliográficos
Main Authors: Linger, Rachel M. A., Keating, Amy K., Earp, H. Shelton, Graham, Douglas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133732/
https://ncbi.nlm.nih.gov/pubmed/18620092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-230X(08)00002-X
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