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Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity

HLA mismatching is an important risk factor for antibody-mediated rejection and transplant failure. With the realization HLA antibodies recognize epitopes rather than antigens, it has become apparent that donor-recipient compatibility should be assessed at the epitope level. Recent developments have...

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Autore principale: Duquesnoy, René J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342002/
https://ncbi.nlm.nih.gov/pubmed/22566848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2011.00059
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