Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates.
Several mono-, di-, tetra-, penta- and nonaribozymes were developed. These multitarget-ribozymes were targeted to cleave HIV-1 env RNA at up to nine different conserved sites. Each multitarget-ribozyme consisted of a chain of up to nine hammerhead motifs, each flanked by a different targeting sequen...
-д хадгалсан:
| -д хэвлэсэн: | Nucleic Acids Res |
|---|---|
| Үндсэн зохиолчид: | , , , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Oxford University Press
1992
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| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.17.4581 |
| Шошгууд: |
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