PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice

BACKGROUND: We have previously demonstrated that peroxisome proliferator-activated receptor (PPARγ) activation inhibits hepatocarcinogenesis. We aim to investigate the effect of PPARγ on hepatocellular carcinoma (HCC) metastatic potential and explore its underlying mechanisms. METHODS: Human HCC cel...

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Hlavní autoři: Shen, B, Chu, E S H, Zhao, G, Man, K, Wu, C-W, Cheng, J T Y, Li, G, Nie, Y, Lo, C M, Teoh, N, Farrell, G C, Sung, J J Y, Yu, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341869/
https://ncbi.nlm.nih.gov/pubmed/22472882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.130
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