Studies on the Dissociation and Urea-Induced Unfolding of FtsZ Support the Dimer Nucleus Polymerization Mechanism

FtsZ is a major protein in bacterial cytokinesis that polymerizes into single filaments. A dimer has been proposed to be the nucleating species in FtsZ polymerization. To investigate the influence of the self-assembly of FtsZ on its unfolding pathway, we characterized its oligomerization and unfoldi...

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Detalhes bibliográficos
Main Authors: Montecinos-Franjola, Felipe, Ross, Justin A., Sánchez, Susana A., Brunet, Juan E., Lagos, Rosalba, Jameson, David M., Monasterio, Octavio
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341561/
https://ncbi.nlm.nih.gov/pubmed/22824282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.064
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