ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero

Previously this laboratory characterized Slc39a8-encoded ZIP8 as a Zn(2+)/(HCO(3) (–))(2) symporter; yet, the overall physiological importance of ZIP8 at the whole-organism level remains unclear. Herein we describe the phenotype of the hypomorphic Slc39a8(neo/neo) mouse which has retained the neomyc...

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Detalhes bibliográficos
Main Authors: Gálvez-Peralta, Marina, He, Lei, Jorge-Nebert, Lucia F., Wang, Bin, Miller, Marian L., Eppert, Bryan L., Afton, Scott, Nebert, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341399/
https://ncbi.nlm.nih.gov/pubmed/22563477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036055
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