Ghrelin Treatment of Cachectic Patients with Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

BACKGROUND: Pulmonary cachexia is common in advanced chronic obstructive pulmonary disease (COPD), culminating in exercise intolerance and a poor prognosis. Ghrelin is a novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy and safety of adding ghrelin to pulmonary re...

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Main Authors: Miki, Keisuke, Maekura, Ryoji, Nagaya, Noritoshi, Nakazato, Masamitsu, Kimura, Hiroshi, Murakami, Shinsuke, Ohnishi, Shunsuke, Hiraga, Toru, Miki, Mari, Kitada, Seigo, Yoshimura, Kenji, Tateishi, Yoshitaka, Arimura, Yasuji, Matsumoto, Nobuhiro, Yoshikawa, Masanori, Yamahara, Kenichi, Kangawa, Kenji
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341383/
https://ncbi.nlm.nih.gov/pubmed/22563468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035708
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