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Nonpolarized signaling reveals two distinct modes of 3D cell migration

We search in this paper for context-specific modes of three-dimensional (3D) cell migration using imaging for phosphatidylinositol (3,4,5)-trisphosphate (PIP3) and active Rac1 and Cdc42 in primary fibroblasts migrating within different 3D environments. In 3D collagen, PIP3 and active Rac1 and Cdc42...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petrie, Ryan J., Gavara, Núria, Chadwick, Richard S., Yamada, Kenneth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341168/
https://ncbi.nlm.nih.gov/pubmed/22547408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201124
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