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Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model

IL-15 has potential as an immunotherapeutic agent for cancer treatment because of its ability to effectively stimulate CD8 T cell, natural killer T cell, and natural killer cell immunity. However, its effectiveness may be limited by negative immunological checkpoints that attenuate immune responses....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yu, Ping, Steel, Jason C., Zhang, Meili, Morris, John C., Waitz, Rebecca, Fasso, Marcella, Allison, James P., Waldmann, Thomas A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341063/
https://ncbi.nlm.nih.gov/pubmed/22474386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203479109
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