Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating

Several polymorphisms of the transcription factor 4 (TCF4) have been shown to increase the risk for schizophrenia, particularly TCF4 rs9960767. This polymorphism is associated with impaired sensorimotor gating measured by prepulse inhibition—an established endophenotype of schizophrenia. We therefor...

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Bibliografische gegevens
Hoofdauteurs: Quednow, Boris B., Brinkmeyer, Jürgen, Mobascher, Arian, Nothnagel, Michael, Musso, Francesco, Gründer, Gerhard, Savary, Noah, Petrovsky, Nadine, Frommann, Ingo, Lennertz, Leonhard, Spreckelmeyer, Katja N., Wienker, Thomas F., Dahmen, Norbert, Thuerauf, Norbert, Clepce, Marion, Kiefer, Falk, Majic, Tomislav, Mössner, Rainald, Maier, Wolfgang, Gallinat, Jürgen, Diaz-Lacava, Amalia, Toliat, Mohammad R., Thiele, Holger, Nürnberg, Peter, Wagner, Michael, Winterer, Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341057/
https://ncbi.nlm.nih.gov/pubmed/22451930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118051109
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