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Intron 1 and the 5'-flanking region of the human thymidylate synthase gene as a regulatory determinant of growth-dependent expression.

We have determined the regulatory regions responsible for the growth-dependent expression of the human thymidylate synthase (TS) gene, using a set of minigenes constructed from segments of the human TS gene and the cDNA clone. Each construct was introduced stably into a TS-negative mutant of rat fib...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Takayanagi, A, Kaneda, S, Ayusawa, D, Seno, T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1992
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.15.4021
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