Troglitazone induced apoptosis of human pterygium fibroblasts through a mitochondrial-dependent pathway

AIM: To study the effect of troglitazone on primary culture human pterygium fibroblasts (HPF). METHODS: Cell viability loss and apoptosis were quantified by cell counting kit-8, AnnexinV-FITC/PI double staining, caspases activity test and western blotting. Flow cytometry was used to detect mitochond...

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Главные авторы: Yang, Xiao-Xi, Chen, Jian, Zhou, Qing, Guo, Xian-Yin, Xiao, Pan, Wu, Jing, Xu, Jin-Tang
Формат: Artigo
Язык:Inglês
Опубликовано: International Journal of Ophthalmology Press 2011
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340713/
https://ncbi.nlm.nih.gov/pubmed/22553629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2011.02.06
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