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Rac1 activates HIF-1 in laser induced choroidal neovascularization

AIM: To study the effect of Rac1 on the induction of HIF-1α in choroidal neovascularization (CNV) in mice. METHODS: One hundred C57BL/6J mice were laser photocoagulated to induce CNV, fifty mice of that were selected randomly for intravitreal injection of Rac1 inhibitor NSC23766 solution (1µL). Afte...

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Detalhes bibliográficos
Main Authors: Zhang, Peng, Zhang, Xing, Fan, Jiang-Li, Hao, Xiao-Feng, Wang, Yu-Sheng, Hui, Yan-Nian, Hu, Dan, Zhou, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340670/
https://ncbi.nlm.nih.gov/pubmed/22553600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2011.01.03
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