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Effects of antioestrogens on the DNA binding activity of oestrogen receptors in vitro.

We have investigated the effect of a series of steroidal oestrogen antagonists, related to ICI 164,384, on the DNA binding activity of mouse oestrogen receptors expressed in insect cells. The analogues possess different side chains at the 7-position of the B ring in the steroid. Inhibition was obser...

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Bibliografiske detaljer
Main Authors: Arbuckle, N D, Dauvois, S, Parker, M G
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334056/
https://ncbi.nlm.nih.gov/pubmed/1508668
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