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A predicted geranylgeranyl reductase reduces the ω-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii

In N-glycosylation in both Eukarya and Archaea, N-linked oligosaccharides are assembled on dolichol phosphate prior to transfer of the glycan to the protein target. However, whereas only the α-position isoprene subunit is saturated in eukaryal dolichol phosphate, both the α- and ω-position isoprene...

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Main Authors: Naparstek, Shai, Guan, Ziqiang, Eichler, Jerry
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340491/
https://ncbi.nlm.nih.gov/pubmed/22469971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.03.002
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