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Linking the Epigenome to the Genome: Correlation of Different Features to DNA Methylation of CpG Islands

DNA methylation of CpG islands plays a crucial role in the regulation of gene expression. More than half of all human promoters contain CpG islands with a tissue-specific methylation pattern in differentiated cells. Still today, the whole process of how DNA methyltransferases determine which region...

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Библиографические подробности
Главные авторы: Wrzodek, Clemens, Büchel, Finja, Hinselmann, Georg, Eichner, Johannes, Mittag, Florian, Zell, Andreas
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340366/
https://ncbi.nlm.nih.gov/pubmed/22558141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035327
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