Phenolic Compounds Prevent Amyloid β-Protein Oligomerization and Synaptic Dysfunction by Site-specific Binding

Cerebral deposition of amyloid β protein (Aβ) is an invariant feature of Alzheimer disease (AD), and epidemiological evidence suggests that moderate consumption of foods enriched with phenolic compounds reduce the incidence of AD. We reported previously that the phenolic compounds myricetin (Myr) an...

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Detalhes bibliográficos
Main Authors: Ono, Kenjiro, Li, Lei, Takamura, Yusaku, Yoshiike, Yuji, Zhu, Lijun, Han, Fang, Mao, Xian, Ikeda, Tokuhei, Takasaki, Jun-ichi, Nishijo, Hisao, Takashima, Akihiko, Teplow, David B., Zagorski, Michael G., Yamada, Masahito
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340280/
https://ncbi.nlm.nih.gov/pubmed/22393064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325456
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