Phenolic Compounds Prevent Amyloid β-Protein Oligomerization and Synaptic Dysfunction by Site-specific Binding

Cerebral deposition of amyloid β protein (Aβ) is an invariant feature of Alzheimer disease (AD), and epidemiological evidence suggests that moderate consumption of foods enriched with phenolic compounds reduce the incidence of AD. We reported previously that the phenolic compounds myricetin (Myr) an...

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Autori principali: Ono, Kenjiro, Li, Lei, Takamura, Yusaku, Yoshiike, Yuji, Zhu, Lijun, Han, Fang, Mao, Xian, Ikeda, Tokuhei, Takasaki, Jun-ichi, Nishijo, Hisao, Takashima, Akihiko, Teplow, David B., Zagorski, Michael G., Yamada, Masahito
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340280/
https://ncbi.nlm.nih.gov/pubmed/22393064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325456
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