The Unfolded Protein Response Regulates an Angiogenic Response by the Kidney Epithelium during Ischemic Stress

Ischemic injuries permanently affect kidney tissue and challenge cell viability, promoting inflammation and fibrogenesis. Ischemia results in nutrient deprivation, which triggers endoplasmic reticulum stress, ultimately resulting in the unfolded protein response (UPR). The aim of this study was to t...

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Bibliographic Details
Main Authors: Bouvier, Nicolas, Fougeray, Sophie, Beaune, Philippe, Thervet, Eric, Pallet, Nicolas
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340272/
https://ncbi.nlm.nih.gov/pubmed/22403402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340570
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