Goodpasture Antigen-binding Protein/Ceramide Transporter Binds to Human Serum Amyloid P-Component and Is Present in Brain Amyloid Plaques

Serum amyloid P component (SAP) is a non-fibrillar glycoprotein belonging to the pentraxin family of the innate immune system. SAP is present in plasma, basement membranes, and amyloid deposits. This study demonstrates, for the first time, that the Goodpasture antigen-binding protein (GPBP) binds to...

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Hauptverfasser: Mencarelli, Chiara, Bode, Gerard H., Losen, Mario, Kulharia, Mahesh, Molenaar, Peter C., Veerhuis, Robert, Steinbusch, Harry W. M., De Baets, Marc H., Nicolaes, Gerry A. F., Martinez-Martinez, Pilar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340266/
https://ncbi.nlm.nih.gov/pubmed/22396542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299545
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