Chronic Expression of RCAN1-1L Protein Induces Mitochondrial Autophagy and Metabolic Shift from Oxidative Phosphorylation to Glycolysis in Neuronal Cells

Expression of the RCAN1 gene can be induced by multiple stresses. RCAN1 proteins (RCAN1s) have both protective and harmful effects and are implicated in common human pathologies. The mechanisms by which RCAN1s function, however, remain poorly understood. We identify RCAN1s as regulators of mitochond...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ermak, Gennady, Sojitra, Sonal, Yin, Fei, Cadenas, Enrique, Cuervo, Ana Maria, Davies, Kelvin J. A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340208/
https://ncbi.nlm.nih.gov/pubmed/22389495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.305342
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