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Crystal Structure of N-Glycosylated Human Glypican-1 Core Protein: STRUCTURE OF TWO LOOPS EVOLUTIONARILY CONSERVED IN VERTEBRATE GLYPICAN-1

Glypicans are a family of cell-surface proteoglycans that regulate Wnt, hedgehog, bone morphogenetic protein, and fibroblast growth factor signaling. Loss-of-function mutations in glypican core proteins and in glycosaminoglycan-synthesizing enzymes have revealed that glypican core proteins and their...

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Detalhes bibliográficos
Main Authors: Svensson, Gabriel, Awad, Wael, Håkansson, Maria, Mani, Katrin, Logan, Derek T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340175/
https://ncbi.nlm.nih.gov/pubmed/22351761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322487
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