The Helicase HAGE Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Cell Proliferation in Vivo

Malignant melanoma-initiating cells (MMIC) are a subpopulation of cells responsible for melanoma tumor growth and progression. They are defined by the expression of the ATP-binding cassette (ABC) subfamily B member 5 (ABCB5). Here, we identified a critical role for the DEAD-box helicase antigen (HAG...

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Autors principals: Linley, Adam J., Mathieu, Morgan G., Miles, Amanda K., Rees, Robert C., McArdle, Stephanie E. B., Regad, Tarik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340133/
https://ncbi.nlm.nih.gov/pubmed/22393060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308973
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