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Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae

Insecticide resistance is an ideal model to study the emergence and spread of adaptative variants. In the African malaria mosquito, Anopheles gambiae, this is complemented by a strong public health rationale. In this insect, resistance to pyrethroid and DDT insecticides is strongly associated with t...

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Autors principals: Jones, Christopher M., Liyanapathirana, Milindu, Agossa, Fiacre R., Weetman, David, Ranson, Hilary, Donnelly, Martin James, Wilding, Craig S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340067/
https://ncbi.nlm.nih.gov/pubmed/22493253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201475109
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