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Transcription by an immobilized RNA polymerase from bacteriophage T7 and the topology of transcription.

It is often assumed that a polymerase moves along the template as it synthesizes RNA. However, a polymerase that tracks along a helical strand will generate a transcript that is entwined about the template. No such interlocking results if the polymerase is immobile and the template moves past it. Th...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Cook, P R, Gove, F
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1992
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1641325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.14.3591
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