Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation

G protein-coupled receptors (GPCRs) have been shown to activate the mitogen-activated protein kinases, ERK1/2, through both G protein-dependent and -independent mechanisms. Here, we describe a G protein-independent mechanism that unravels an unanticipated role for β-arrestins. Stimulation of the V2...

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Bibliografiska uppgifter
Huvudupphovsmän: Oligny-Longpré, Geneviève, Corbani, Maithé, Zhou, Joris, Hogue, Mireille, Guillon, Gilles, Bouvier, Michel
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340024/
https://ncbi.nlm.nih.gov/pubmed/22493236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112422109
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