Cardiac Lineage Protein-1 (CLP-1) Regulates Cardiac Remodeling via Transcriptional Modulation of Diverse Hypertrophic and Fibrotic Responses and Angiotensin II-transforming Growth Factor β (TGF-β1) Signaling Axis

It is well known that the renin-angiotensin system contributes to left ventricular hypertrophy and fibrosis, a major determinant of myocardial stiffness. TGF-β1 and renin-angiotensin system signaling alters the fibroblast phenotype by promoting its differentiation into morphologically distinct patho...

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Main Authors: Mascareno, Eduardo, Galatioto, Josephine, Rozenberg, Inna, Salciccioli, Louis, Kamran, Haroon, Lazar, Jason M., Liu, Fang, Pedrazzini, Thierry, Siddiqui, M. A. Q.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339995/
https://ncbi.nlm.nih.gov/pubmed/22308025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.288944
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