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Structure of Salmonella Effector Protein SopB N-terminal Domain in Complex with Host Rho GTPase Cdc42

SopB is a type III secreted Salmonella effector protein with phosphoinositide phosphatase activity and a distinct GTPase binding domain. The latter interacts with host Cdc42, an essential Rho GTPase that regulates critical events in eukaryotic cytoskeleton organization and membrane trafficking. Stru...

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Détails bibliographiques
Auteurs principaux: Burkinshaw, Brianne J., Prehna, Gerd, Worrall, Liam J., Strynadka, Natalie C. J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339929/
https://ncbi.nlm.nih.gov/pubmed/22362774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331330
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