An Allele of Microtubule-Associated Protein 1A (Mtap1a) Reduces Photoreceptor Degeneration in Tulp1 and Tub Mutant Mice

PURPOSE. To identify genes that modify photoreceptor cell loss in the retinas of homozygous Tulp1(tm1Pjn) and Tub(tub) mice, which exhibit juvenile retinitis pigmentosa. METHODS. Modifier loci were identified by genetic quantitative trait locus analysis. F2 Tulp1(tm1Pjn/tm1Pjn) mutant mice from a B6...

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Hauptverfasser: Maddox, Dennis M., Ikeda, Sakae, Ikeda, Akihiro, Zhang, Weidong, Krebs, Mark P., Nishina, Patsy M., Naggert, Jürgen K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339923/
https://ncbi.nlm.nih.gov/pubmed/22323461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8871
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