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Sustained Ocular Delivery of Ciprofloxacin Using Nanospheres and Conventional Contact Lens Materials

PURPOSE. To formulate conventional contact lenses that incorporate nanosphere-encapsulated antibiotic and demonstrate that the lenses provide for sustained antibacterial activity. METHODS. A copolymer composed of pullulan and polycaprolactone (PCL) was used to synthesize core-shell nanospheres that...

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Detalhes bibliográficos
Main Authors: Garhwal, Rahul, Shady, Sally F., Ellis, Edward J., Ellis, Jeanne Y., Leahy, Charles D., McCarthy, Stephen P., Crawford, Kathryn S., Gaines, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339908/
https://ncbi.nlm.nih.gov/pubmed/22266514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8215
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