Displacement-encoded and manganese-enhanced cardiac MRI reveal that nNOS, not eNOS, plays a dominant role in modulating contraction and calcium influx in the mammalian heart

Within cardiomyocytes, endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) are thought to modulate L-type calcium channel (LTCC) function and sarcoplasmic reticulum calcium cycling, respectively. However, divergent results from mostly invasive prior studies suggest mor...

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Autori principali: Vandsburger, Moriel H., French, Brent A., Kramer, Christopher M., Zhong, Xiaodong, Epstein, Frederick H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
Soggetti:
Muscle Mechanics and Ventricular Function
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339858/
https://ncbi.nlm.nih.gov/pubmed/22058155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00705.2011
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