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ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

An indolent non-healing wound and insulin and/or insulin-like growth factor (IGF1) resistance are cardinal features of diabetes, inflammation and hypercortisolemia. Little is known about why these phenomena occur in so many contexts. Do the various triggers that induce insulin and/or IGF1 resistance...

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Autores principales: Bitar, Milad S., Al-Mulla, Fahd
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339831/
https://ncbi.nlm.nih.gov/pubmed/22362362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007872
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