Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice

Mouse models of chronic obstructive pulmonary disease (COPD) focus on airway inflammation and lung histology, but their use has been hampered by the lack of pulmonary function data in their assessment. Systemic effects such as muscle dysfunction are also poorly modeled in emphysematous mice. We aime...

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Main Authors: Rinaldi, Manuela, Maes, Karen, De Vleeschauwer, Stéphanie, Thomas, Debby, Verbeken, Erik K., Decramer, Marc, Janssens, Wim, Gayan-Ramirez, Ghislaine N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists Limited 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339827/
https://ncbi.nlm.nih.gov/pubmed/22279084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008508
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