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HDAC4 regulates neuronal survival in normal and diseased retinas

Histone deacetylase 4 (HDAC4) shuttles between the nucleus and cytoplasm, and serves as a nuclear corepressor that regulates bone and muscle development. We report that HDAC4 regulates the survival of retinal neurons in the mouse in normal and pathological conditions. Reduction in HDAC4 expression d...

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Bibliografische gegevens
Hoofdauteurs: Chen, Bo, Cepko, Constance L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339762/
https://ncbi.nlm.nih.gov/pubmed/19131628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166226
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