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HDAC4 regulates neuronal survival in normal and diseased retinas
Histone deacetylase 4 (HDAC4) shuttles between the nucleus and cytoplasm, and serves as a nuclear corepressor that regulates bone and muscle development. We report that HDAC4 regulates the survival of retinal neurons in the mouse in normal and pathological conditions. Reduction in HDAC4 expression d...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339762/ https://ncbi.nlm.nih.gov/pubmed/19131628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166226 |
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