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HDAC4 regulates neuronal survival in normal and diseased retinas

Histone deacetylase 4 (HDAC4) shuttles between the nucleus and cytoplasm, and serves as a nuclear corepressor that regulates bone and muscle development. We report that HDAC4 regulates the survival of retinal neurons in the mouse in normal and pathological conditions. Reduction in HDAC4 expression d...

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Detalles Bibliográficos
Main Authors: Chen, Bo, Cepko, Constance L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339762/
https://ncbi.nlm.nih.gov/pubmed/19131628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166226
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