Development and Validation of a Simple, Rapid and Inexpensive PCR-RFLP Method for Genotyping of Common IL28B Polymorphisms: A Useful Pharmacogenetic Tool for Prediction of Hepatitis C Treatment Response

BACKGROUND: In 2009, 3 genome-wide association studies implicated IL28B single-nucleotide polymorphisms (SNPs) as the strongest genetic pretreatment predictor of sustained virological response (SVR) in hepatitis C infection. Recently, the American Association for the Study of Liver Diseases (AASLD)...

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Autors principals: Sharafi, Heidar, Pouryasin, Ali, Alavian, Seyed Moayed, Behnava, Bita, Keshvari, Maryam, Mehrnoush, Leila, Salimi, Shima, Kheradvar, Osveh
Format: Artigo
Idioma:Inglês
Publicat: Kowsar 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339419/
https://ncbi.nlm.nih.gov/pubmed/22550527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/hepatmon.849
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