Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

We examine whether Phellodendron amurense (PA) and its major alkaloid compound, berberine (BER), improved memory defects caused by administering scopolamine in rats. Effects of PA and BER on the acetylcholinergic system and pro-inflammatory cytokines in the hippocampus were also investigated. Male r...

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Autores principales: Lee, Bombi, Sur, Bongjun, Shim, Insop, Lee, Hyejung, Hahm, Dae-Hyun
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2012
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339292/
https://ncbi.nlm.nih.gov/pubmed/22563252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2012.16.2.79
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