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Effects of the Incorporation of a Hydrophobic Middle Block into a PEG-Polycation Diblock Copolymer on the Physicochemical and Cell Interaction Properties of the Polymer-DNA Complexes

One-component homopolymers of cationic monomers (polycations) and diblock copolymers comprising poly(ethylene glycol) (PEG) and a polycation block have been the most widely used types of polymers for formulation of polymer-based gene delivery systems. In this study, we incorporate a hydrophobic midd...

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Detalhes bibliográficos
Main Authors: Sharma, Rahul, Lee, Jae-Sung, Bettencourt, Ryan C., Xiao, Chuan, Konieczny, Stephen F., Won, You-Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339030/
https://ncbi.nlm.nih.gov/pubmed/18942877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm800876v
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