Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

Our understanding of Alzheimer’s disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model the sporadic form of the disease. It may be possible to overcome these challenges by reprogramming primary cells from patients into induced pl...

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Detalhes bibliográficos
Main Authors: Israel, Mason A., Yuan, Shauna H., Bardy, Cedric, Reyna, Sol M., Mu, Yangling, Herrera, Cheryl, Hefferan, Michael P., Van Gorp, Sebastiaan, Nazor, Kristopher L., Boscolo, Francesca S., Carson, Christian T., Laurent, Louise C., Marsala, Martin, Gage, Fred H., Remes, Anne M., Koo, Edward H., Goldstein, Lawrence S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338985/
https://ncbi.nlm.nih.gov/pubmed/22278060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10821
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