A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors

Angiomotin (Amot) is one of several identified angiostatin receptors expressed by the endothelia of angiogenic tissues. We have shown that a DNA vaccine targeting Amot overcome immune tolerance and induce an antibody response that hampers the progression of incipient tumors. Following our observatio...

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Detalhes bibliográficos
Main Authors: Arigoni, Maddalena, Barutello, Giuseppina, Lanzardo, Stefania, Longo, Dario, Aime, Silvio, Curcio, Claudia, Iezzi, Manuela, Zheng, Yujuan, Barkefors, Irmeli, Holmgren, Lars, Cavallo, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338916/
https://ncbi.nlm.nih.gov/pubmed/22426512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9263-3
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