Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

OBJECTIVE: Enhanced adhesive signaling including activation of the focal adhesion kinase (FAK) is a hallmark of fibroblasts from lung fibrosis patients, and FAK has been therefore hypothesized to be a key mediator of this disease. This study was undertaken to characterize the contribution of FAK to...

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Autori principali: Lagares, David, Busnadiego, Oscar, García-Fernández, Rosa Ana, Kapoor, Mohit, Liu, Shangxi, Carter, David E., Abraham, David, Shi-Wen, Xu, Carreira, Patricia, Fontaine T, Benjamin A, Shea, Barry S, Tager, Andrew M, Leask, Andrew, Lamas, Santiago, Rodríguez-Pascual, Fernando
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338902/
https://ncbi.nlm.nih.gov/pubmed/22492165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33482
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