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L1pred: A Sequence-Based Prediction Tool for Catalytic Residues in Enzymes with the L1-logreg Classifier

To understand enzyme functions, identifying the catalytic residues is a usual first step. Moreover, knowledge about catalytic residues is also useful for protein engineering and drug-design. However, to experimentally identify catalytic residues remains challenging for reasons of time and cost. Ther...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dou, Yongchao, Wang, Jun, Yang, Jialiang, Zhang, Chi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338704/
https://ncbi.nlm.nih.gov/pubmed/22558194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035666
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