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Fibroblast Growth Factor Signaling Deficiencies Impact Female Reproduction and Kisspeptin Neurons in Mice

Fibroblast growth factor (FGF) signaling is essential for the development of the gonadotropin-releasing hormone (GnRH) system. Mice harboring deficiencies in Fgf8 or Fgf receptor 1 (Fgfr1) suffer a significant loss of GnRH neurons, but their reproductive phenotypes have not been examined. This study...

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Bibliografiska uppgifter
Huvudupphovsmän: Tata, Brooke K., Chung, Wilson C.J., Brooks, Leah R., Kavanaugh, Scott I., Tsai, Pei-San
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for the Study of Reproduction, Inc 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338661/
https://ncbi.nlm.nih.gov/pubmed/22278983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.095992
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