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Male Differentiation of Germ Cells Induced by Embryonic Age-Specific Sertoli Cells in Mice
Retinoic acid (RA) is a meiosis-inducing factor. Primordial germ cells (PGCs) in the developing ovary are exposed to RA, resulting in entry into meiosis. In contrast, PGCs in the developing testis enter mitotic arrest to differentiate into prospermatogonia. Sertoli cells express CYP26B1, an RA-metab...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for the Study of Reproduction, Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338658/ https://ncbi.nlm.nih.gov/pubmed/22262692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.095943 |
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