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The Autoimmune Regulator Prevents Premature Reproductive Senescence in Female Mice
Loss-of-function mutations in the autoimmune regulator (AIRE) gene are responsible for autoimmune polyglandular syndrome type 1 (APS-1), which commonly manifests as infertility in women. AIRE is a transcriptional regulator that promotes expression of tissue-restricted antigens in the thymus, includi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for the Study of Reproduction, Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338656/ https://ncbi.nlm.nih.gov/pubmed/22219212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.097501 |
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