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Mutations of the Mouse ELMO Domain Containing 1 Gene (Elmod1) Link Small GTPase Signaling to Actin Cytoskeleton Dynamics in Hair Cell Stereocilia

Stereocilia, the modified microvilli projecting from the apical surfaces of the sensory hair cells of the inner ear, are essential to the mechanoelectrical transduction process underlying hearing and balance. The actin-filled stereocilia on each hair cell are tethered together by fibrous links to fo...

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Autori principali: Johnson, Kenneth R., Longo-Guess, Chantal M., Gagnon, Leona H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338648/
https://ncbi.nlm.nih.gov/pubmed/22558334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036074
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