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Are Coiled-Coils of Dimeric Kinesins Unwound during Their Walking on Microtubule?

Dimeric kinesin motor proteins such as homodimeric kinesin-1, homodimeric Ncd and heterodimeric Kar3/Vik1are composed of two head domains which are connected together by a rod-shaped, coiled-coil stalk. Despite the extensive and intensive studies on structures, kinetics, dynamics and walking mechani...

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Detalhes bibliográficos
Main Authors: Duan, Zhao-Wen, Xie, Ping, Li, Wei, Wang, Peng-Ye
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338639/
https://ncbi.nlm.nih.gov/pubmed/22558333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036071
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