Protective Efficacy of Neutralizing Monoclonal Antibodies in a Nonhuman Primate Model of Ebola Hemorrhagic Fever

Ebola virus (EBOV) is the causative agent of severe hemorrhagic fever in primates, with human case fatality rates up to 90%. Today, there is neither a licensed vaccine nor a treatment available for Ebola hemorrhagic fever (EHF). Single monoclonal antibodies (MAbs) specific for Zaire ebolavirus (ZEBO...

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Bibliographic Details
Main Authors: Marzi, Andrea, Yoshida, Reiko, Miyamoto, Hiroko, Ishijima, Mari, Suzuki, Yasuhiko, Higuchi, Megumi, Matsuyama, Yukie, Igarashi, Manabu, Nakayama, Eri, Kuroda, Makoto, Saijo, Masayuki, Feldmann, Friederike, Brining, Douglas, Feldmann, Heinz, Takada, Ayato
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338609/
https://ncbi.nlm.nih.gov/pubmed/22558378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036192
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