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Inherent Interfacial Mechanical Gradients in 3D Hydrogels Influence Tumor Cell Behaviors
Cells sense and respond to the rigidity of their microenvironment by altering their morphology and migration behavior. To examine this response, hydrogels with a range of moduli or mechanical gradients have been developed. Here, we show that edge effects inherent in hydrogels supported on rigid subs...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338483/ https://ncbi.nlm.nih.gov/pubmed/22558241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035852 |
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