Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

Bidirectional axonal transport driven by kinesin and dynein along microtubules is critical to neuronal viability and function. To evaluate axonal transport mechanisms, we developed a high-resolution imaging system to track the movement of amyloid precursor protein (APP) vesicles in Drosophila segmen...

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Detalhes bibliográficos
Main Authors: Reis, Gerald F., Yang, Ge, Szpankowski, Lukasz, Weaver, Carole, Shah, Sameer B., Robinson, John T., Hays, Thomas S., Danuser, Gaudenz, Goldstein, Lawrence S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338437/
https://ncbi.nlm.nih.gov/pubmed/22398725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0938
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